To investigate the predictive value of MRI diffusion-weighted imaging (DWI) features in acute cerebral infarction in intracranial hemorrhage after endovascular thrombectomy. Methods: 107 patients with acute cerebral infarction treated from August 2021 to December 2023 were selected. Group according to the presence of intracranial hemorrhage after endovascular thrombectomy. General patient data were collected and the RAPID software was used to automatically calculate the DWI infarction volume and Tmax. Results: There was no difference between the data from onset to admission, EVT, and intravenous thrombolysis (P> 0.05), but fasting blood glucose, HbAlc level and DWI value were significantly higher than no bleeding (P <0.05). Logistic Regression analysis found that Hb Alc, fasting blood glucose level, and DWI infarct volume were independent predictors of bleeding after endovascular thrombectomy in patients with acute cerebral infarction (P <0.05). Conclusion: MRI diffusion-weighted imaging features, fasting blood glucose, and HbA 1 c can be the predictors of intracranial hemorrhage after endovascular thrombectomy and are significantly associated with the risk of postoperative intracranial hemorrhage.