Objective: To explore the visualization effect and imaging clarity of magnetic resonance T2 sequence and SWI sequence in the Subthalamic Nucleus (STN), to study the error between the surgical target located by different sequences and the actual target, and to calculate the error amount, to guide the preoperative surgical planning and imaging selection. Research methods: A total of 11 patients, who received DBS surgery for Parkinson""s disease in the Department of Neurosurgery of the First Affiliated Hospital of Henan University from December 2018 to December 2020 and who met the inclusion criteria of this study were collected and analyzed. After rigorous preoperative evaluation, all patients received preoperative 3.0T magnetic resonance Imaging, and 3DT1 Bravo, T2, and Susceptibility Weighted Imaging (SWI) sequences were scanned. T2 sequence and SWI sequence were used to formulate the surgical plan and generate the corresponding surgical coordinates. All patients received bilateral subthalamic nucleus deep brain electrode implantation, a total of 22 sides. High-resolution thin-layer craniocerebral CT was reexamined postoperatively and fused with preoperative MRI. The location coordinates of the electrode tip were reconstructed after surgery and compared with the coordinates of the T2 plan and the coordinates of the SWI plan respectively to analyze the error values. Results: The Z-axis difference between T2 and SWI coordinates on both sides is calculated and compared. The result is that the left SWI is 2.16±1.02mm deeper than T2. The right SWI is 2.13±1.62mm deeper than T2. Conclusions: 1. SWI sequences show superiority over T2 sequences in terms of imaging effect and boundary display of target nucleus. 2. The depth of STN in the SWI sequence is about 2mm deeper than that in the T2 sequence, and it is more consistent with the electrophysiological depth. 3. The actual implanted electrode coordinates are backward compared to the T2 planned coordinates，However, there is no significant difference between the actual coordinates and the SWI sequence planning coordinates.