前交通动脉瘤形态学与血流动力学研究进展
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1.赣南医学院第一附属医院神经外科 2.赣南医学院教育部心脑血管病重点实验室

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Research progress on morphology and hemodynamics of anterior communicating artery aneurysms
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    摘要:

    前交通动脉瘤是颅内动脉瘤中最常见的类型,一旦破裂,往往症状剧烈,预后不良。近年来,随着影像三维重建技术的发展和计算流体力学的兴起,前交通动脉瘤起始、发展、破裂过程中相关形态学特征及异常血流动力学变化逐渐被揭示。研究表明,前交通动脉瘤的最大径、纵横比、大小比等特征有助于预测破裂风险、大脑前动脉一侧A1段发育不良以及A1段、A2段夹角与前交通动脉瘤的发生发展有关、血流动力学改变在动脉瘤形成和破裂中起重要作用。本文对前交通动脉瘤形态学特征和异常血流动力学变化之间的联系进行综述,探讨两者之间相互作用的内在机制,为前交通动脉瘤的早期防治提供依据以及新的思路。

    Abstract:

    Anterior communicating artery aneurysm is the most common type of intracranial aneurysm. Once ruptured, the symptoms are often severe and the prognosis is adverse. In recent years, with the development of imaging 3D reconstruction technology and the rise of computational fluid dynamics, related morphological features and abnormal hemodynamic changes during the initiation, development and rupture of anterior communicating artery aneurysms have been gradually revealed. Studies have shown that the characteristics of the largest diameter, aspect ratio, and size ratio of anterior communicating artery aneurysms can help predict the risk of rupture, dysplasia of the A1 segment on one side of the anterior cerebral artery, and the angle between the A1 and A2 segments of the anterior cerebral artery and anterior communicating artery aneurysm. Hemodynamic changes play an important role in the formation and rupture of aneurysms. This article reviews the relationship between the morphological characteristics of anterior communicating artery aneurysms and abnormal hemodynamic changes, and discusses the internal mechanism of the interaction between them, so as to provide evidence and new ideas for the early prevention and treatment of anterior communicating artery aneurysms.

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  • 收稿日期:2022-03-08
  • 最后修改日期:2022-04-20
  • 录用日期:2022-05-05
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