以脑膜转移为主要表现的隐匿性结肠癌一例
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1.河北省人民医院;2.河北医科大学研究生学院;3.河北省人民医院神经内科

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2020河北省高端人才资助项目(83587216);2019河北省政府资助临床医学优秀人才培养项目(冀财社:2019-139-5)


A case of occult colon cancer with?the?main?manifestation?of meningeal metastasis
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    摘要:

    脑膜癌病(MC)是指恶性肿瘤播散或浸润软脑(脊)膜、蛛网膜下腔,而脑实质不受累的一类疾病,为中枢神经系统转移瘤的少见类型,在实体瘤患者中发生率极低。MC起病隐袭,症状复杂无特异性,患者可呈头痛、意识改变及多种神经功能缺损表现,对于原发灶不明而以脑病为首发症状者,极易误诊、漏诊。现就1例以脑膜转移为首发表现、原发灶为结肠腺癌患者的临床资料进行分析,旨在提高对此病的警惕和认识。

    Abstract:

    Meningeal carcinomatosis (MC) is a kind of disease in which malignant tumor spreads or infiltrates the soft brain (spinal) membrane and subarachnoid space, but leaves the brain parenchyma uninvolved. It is a rare type of metastases of the central nervous system and shows a low incidence in solid tumor patients. With a hidden onset, MC usually displays complicated but non-specific symptoms. Patients may present with headache, consciousness change and various neurological defects. For patients with unclear primary focus and encephalopathy as the initial symptom, it is easy to be missed or wrongly diagnosed. This article analyzes the clinical data of a patient with meningeal metastasis as the primary manifestation of colorectal adenocarcinoma, in order to improve the vigilance and understanding of this disease.

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  • 收稿日期:2022-01-03
  • 最后修改日期:2022-04-07
  • 录用日期:2022-05-05
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