Objective To investigate the efficacy and safety of gamma knife radiosurgery （GKRS） in the treatment of perioptic cavernous sinus hemangiomas （CaSHs）.Methods An analysis was performed for the clinical data of 11 patients who received GKRS for the treatment of perioptic CaSHs in Shanghai Gamma Hospital from March 2018 to September 2020， among whom 10 patients were diagnosed based on magnetic resonance imaging and 1 patient was diagnosed based on histopathology after endonasal transsphenoidal surgery. There were 10 female patients with a median age of 40 （range 27-72） years. Tumor volume ranged from 5.54 cm³ to 31.00 cm³， with a median tumor volume of 15.09 cm³. All 11 patients underwent two-dose-staged GKRS， with a median interval of 8 months （range 3-9 months） between the two stages of GKRS. In the first stage of GKRS， the peripheral dose of gamma knife was 8-10 Gy （median 8.8 Gy）， with an isodose contour of 40%-50% （median 45%）； in the second stage of GKRS， the peripheral dose of gamma knife was 8-10 Gy （median 8.8 Gy）， with an isodose contour of 40%-52% （median 46%）.Results The patients were followed up for 25-60 months （median 40 months） after GKRS. Tumor volume was reduced by 20.3%-85.3% （median 64.2%） from the first stage to the second stage of GKRS. At the end of follow-up， all 11 patients achieved tumor control， with a control rate of 100%， and tumor volume was reduced by 70.6%-92.5% （median 83.0%） after GKRS. Of all 11 patients， 10 （90.9%） had disappearance or improvement of their clinical symptoms after GKRS， and no radiation-induced optic neuropathy or neurological dysfunction was observed during follow-up.Conclusions Dose-staged GKRS is an effective， safe， and reasonable treatment strategy for perioptic CaSHs.