Late-onset epilepsy （LOE） refers to newly diagnosed epilepsy in elderly people aged 65 years and above. The prevalence and incidence rates of LOE are increasing year by year. However， few clinical studies have investigated this condition， and the clinical management of patients with LOE faces challenges. This review presents the definition， epidemiological data， etiology， clinical manifestations， diagnosis， differential diagnosis， and treatment of LOE on the basis of literature on LOE in the recent decade. We hope to provide some guidance for standardized management of patients with LOE in clinical practice. ［Journal of International Neurology and Neurosurgery, 2023, 50(6): 68-71］