Traumatic brain injury is a common type of injury， and there are often changes in the mechanism of bleeding and the balance of thrombosis after severe traumatic brain injury. Impaired hemostasis may exacerbate primary injury and have the risk of inducing or aggravating bleeding. Many patients with traumatic brain injury are found to have abnormalities in conventional coagulation tests on admission， while further studies are needed to clarify the extent to which these coagulation abnormalities affect the prognosis of severe traumatic brain injury and whether they are modifiable risk factors. For the research on coagulation disorders， thromboelastography is used in China and globally to more accurately reflect the association between coagulation disorders and the severity of traumatic brain injury. This article reviews the current status of the research on coagulation disorders and severe traumatic brain injury. ［Journal of International Neurology and Neurosurgery, 2022, 49(6): 102-106］