With the development of endoscopic equipment and technology in recent years， endoscopic transnasal skull base surgery has been more widely used in clinical practice. Postoperative cerebrospinal fluid leak is one of the main complications of this technique and is an important factor restricting the development of endoscopic transnasal skull base surgery. Accurate and reliable skull base reconstruction technique can effectively reduce postoperative cerebrospinal fluid leak and improve the effect of endoscopic transnasal skull base surgery. This article reviews the materials， technical methods， and related advances in skull base reconstruction.