Hereditary hemorrhagic telangiectasia （HHT） is a rare autosomal dominant hereditary disease and often manifests as nosebleed， gastrointestinal bleeding， anemia， hepatic/cerebral/pulmonary arteriovenous malformation， and vasodilation of the skin and mucosa. There are currently no reports on the cases of HHT complicated by multiple cerebral hemorrhage events in China. This article reports a case of HHT complicated by multiple cerebral hemorrhage events successfully treated by integrated traditional Chinese and Western medicine therapy and summarizes the onset， progression， diagnosis， and treatment of this patient， and a literature review was also performed， so as to improve the clinical treatment rate of such patients.