In recent years， the premonitory stage of migraine has attracted much attention due to its role in prediction of headache and intervention of early-stage headache. Yawning， fatigue， neck stiffness， and sensory hyper excitability （photophobia， phonophobia， and osmophobia） are common premonitory symptoms in migraine. However， no unified conclusion has been reached on the predictive performance of premonitory symptoms in migraine and possible mechanism. The premonitory symptoms in migraine can be classified as sensory hypersensitivity symptoms， sleep- and cognition-related symptoms， autonomic symptoms， and other symptoms. No consensus has been reached on the precise distinction between premonitory symptoms/triggers and associated symptoms of migraine. Fatigue， mood changes， and neck stiffness are common premonitory symptoms in adolescents. At present， the research on the path physiological mechanism of premonitory symptoms in migraine is still in the preliminary stage. Yawning is one of the premonitory symptoms in migraine with predictive significance， which is generally believed to be closely associated with the changes in dopaminergic neurons， and in the path physiology of migraine， it can be mediated by dopaminergic D1， D2， and D3 receptors. Neck stiffness is a common premonitory symptom of migraine， which is associated with the activation of dopaminergic and serotonergic neurons， and the hypothalamusis activated in the premonitory phase of migraine， which may be an important cause of neck stiffness in the premonitory phase. Nausea is another common premonitory symptom in migraine， but there are still controversies over its pathophysiological origin， and current studies have shown that nausea in the premonitory phase is associated with the metabolic change in 5-hydroxytryptamine. The symptoms of sensory hyper excitability include cutaneous allodynia， photophobia， phonophobia， and osmophobia， and the activation of the thalamus in the premonitory phase has been proved to be associated with cutaneous allodynia and photophobia in migraine.