Alzheimer’s disease （AD） is a neurodegenerative disease characterized by progressive cognitive impairment， impairment of daily activities， and personality changes， which brings a heavy burden on families and society. Mild cognitive impairment （MCI） is the transition stage between healthy aging and AD. Current pharmacotherapy for cognitive impairment has an unsatisfactory clinical effect， and effective non-pharmaceutical interventions should be actively explored before the marketing of effective pharmaceutical interventions. An increasing number of evidence has shown that cognitive interventions can effectively alleviate cognitive impairment caused by AD and may also be used to prevent the development of AD in healthy elderly people. This article summarizes related studies and possible mechanisms of cognitive intervention， provides suggestions for the future application of cognitive intervention， and develops the technical specifications for individualized intelligent rehabilitation therapy for patients with cognitive impairment.