Abstract:Objective To explore the strategy of LVIS stent-assisted coil embolization in treating ruptured wide-necked intracranial aneurysms in the acute stage. Methods A retrospective analysis was performed on the clinical data of 17 patients with ruptured wide-necked intracranial aneurysms (a total of 19 aneurysms) who were treated with LVIS stent-assisted coil embolization from January 2017 to December 2019. Before the operation, all patients received oral or rectal administration of aspirin and clopidogrel, each at a dose of 300 mg. During the operation, conventional heparinization was performed. The Raymond classification was used to assess the effectiveness of embolization. After the operation, all patients received oral administration of aspirin (100 mg/d for 6 months) and clopidogrel (75 mg/d for 3 months). The modified Rankin Scale (mRS) was used to evaluate the clinical efficacy, and grade 0~2 represented a good prognosis. Results In this group of patients, 17 stents were completely released, with a success rate of 100%. The angiography immediately after embolization showed that all the aneurysms were completely occluded. Two patients (11.8%) developed intracranial vascular embolism during the embolization therapy. After 5~10 mL of tirofiban injection, the vessels were recanalized. After the operation, one patient died of respiratory failure, and another died of acute myocardial infarction. Among the surviving patients, the prognostic mRS score was as follows:0 in 5 cases, 1 in 3 cases, 2 in 6 cases, and 3 in 1 case, with a good prognosis rate of 88.2%. No stent-related adverse events occurred. Conclusions LVIS stent-assisted coil embolization has a good effect in treating ruptured wide-necked aneurysms in the acute stage, but its risk and long-term efficacy still need large-sample studies and follow-up.