Based on micro-vibration generated by piezoelectric effect, piezosurgery (PS) can achieve precise and selective bone cutting without damaging the structure of the surrounding soft tissue, with high safety and easy operation, and therefore, it is widely used in many surgical fields including craniomaxillofacial surgery. In recent years, PS has been proved to be safe and effective in various types of supratentorial and infratentorial craniotomy in neurosurgery, with low incidence rates of postoperative complications such as dural injury, venous sinus injury, and cerebrospinal fluid leakage, and meanwhile, it can reduce bone loss, achieve good cosmetic and hemostatic effects, and keep the surgical field clear.