Objective To investigate the binocular rivalry alternation rate and its possible neural mechanism in patients with Parkinson's disease (PD) using binocular rivalry paradigm.Methods A total of 32 idiopathic PD patients with a confirmed diagnosis were enrolled as PD group, and 32 healthy controls matched for demographic data were enrolled as HC group. To assess the binocular rivalry alternating rate using binocular rivalry test.Results The PD group had a significantly lower binocular rivalry alternation rate than the HC group (0.24±0.07 Hz vs 0.35±0.11 Hz, t=-4.653, P=0.000).Conclusions PD patients have a significantly lower binocular rivalry alternation rate than healthy controls, which may be associated with weakened perceptual alteration caused by frontal lobe-basal ganglia nerve pathway injury.