Objective To investigate the status and influencing factors for mild cognitive impairment (MCI) among elderly senior intellectuals in Tianjin, China.Methods The Montreal Cognitive Assessment (MoCA) Scale was administered to 2105 elderly senior intellectuals who underwent physical examination in the physical examination center of a grade-A tertiary hospital in Tianjin. Univariate and multivariate logistic regression analyses were used for identifying influencing factors for MCI.Results The MoCA score averaged 26.81±1.85 in the 2105 participants, and 402 cases of MCI (19.10%) were detected. The univariate logistic regression analysis showed that sex (χ²=21.23, P<0.01) and triglyceride abnormality (χ²=5.84, P<0.05) were influencing factors for MCI in the elderly. The multivariate logistic regression analysis showed that female sex (odds ratio[OR]=0.29, 95% confidence interval[CI]:0.42-0.70), not drinking wine (OR=0.63, 95%CI:0.40-0.99), and triglyceride abnormality (OR=1.34, 95%CI:1.09-1.71) entered the regression model.Conclusions Female sex and not drinking wine are protective factors against MCI, while triglyceride abnormality is a risk factor among elderly senior intellectuals in Tian. Targeted prevention can be carried out according to the influencing factors.