Neurology is based on the complex anatomical structures of the nervous system and has strong professionalism, and therefore, it is hard to establish a systematic, complete, and stereoscopic knowledge system of the neural network in the learning process. Medical students think it is difficult to understand such abstract knowledge and thus cannot achieve knowledge internalization and analysis and diagnosis. With the advent of mobile Internet, cloud computing, big data, artificial intelligence, and the 5G era, the information technology in China is experiencing rapid development and great changes. Massive open online course (MOOC) is the latest development of distance education. It is developed through open educational resources, and students can learn online courses through the Internet. The MOOC-based flipped classroom teaching is a new teaching model with the deep integration of information technology and higher education teaching. In addition to breaking the traditional cramming teaching model, this model introduces the student-centered and teacher-led classroom teaching methods to fully mobilize the enthusiasm and subjective initiative of learning and truly achieve the education concept centered on students' development, and thus it is possible to reasonably increase the difficulty and expand the depth and selectivity of the course.