Objective To summarize the experience in the application of LVIS stents in embolization therapy for posterior-circulation aneurysms. Methods A retrospective analysis was performed for the clinical data of 24 patients with posterior-circulation aneurysms who underwent LVIS stent-assisted embolization and were followed up in our hospital. Results All 24 patients underwent successful embolization. A total of 35 stents were used in the 24 patients, including 32 LVIS stents. Of all patients, 4 received dual LVIS stents alone, 13 received single LVIS stent-assisted coil embolization, 3 received Enterprise stent+LVIS stent-assisted coil embolization, and 4 received dual LVIS stent-assisted coil embolization. The success rate of stent implantation was 100%, and there were 2 cases of poor opening of the tail end, which were opened well after massage with stent catheter. No reduction or constriction was observed in the arterial branches covered by the stents. No in-stent stenosis or occlusion of the artery with aneurysm was observed. Routine radiographic examination was performed according to the modified Raymond classification after embolization, and the results showed grade I in 18 patients, grade Ⅱ in 2 patients, and grade Ⅲ in 4 patients. Intraoperative rupture was observed in 1 patient, and postoperative acute cerebral infarction was observed in 1 patient. At the time of discharge, the Glasgow Outcome Scale score was 5 points in 17 patients, 4 points in 1 patient, 3 points in 2 patients, 2 points in 3 patients, and 1 point in 1 patient. Among the 13 patients who underwent reexamination, 1 experienced recurrence. Conclusions LVIS stents are safe and effective in the treatment of posterior-circulation aneurysms and can achieve good outcomes.