Abstract:Objective To investigate the association between left ventricular diastolic dysfunction and acute cerebral infarction in young patients with hypertension.Methods A total of 92 young patients with acute cerebral infarction and hypertension who were admitted to Department of Neurology in Baoji Second Hospital of Traditional Chinese Medicine from October 2014 to February 2018 were enrolled as observation group, and 98 young patients with hypertension who underwent physical examination during the same period of time were enrolled as control group. Heart color Doppler was performed for both groups to observe left ventricular diastolic function and analyze the association between left ventricular diastolic dysfunction and acute cerebral infarction.Results Among the 190 young patients with hypertension, 18 (9.47%) had normal left ventricular diastolic function and 172 (90.53%) had reduced left ventricular diastolic function, among whom 127 (127/190, 66.84%) had grade 1 left ventricular diastolic function, 55 (55/190, 28.95%) had grade 2 left ventricular diastolic function, and 8 (8/190, 4.21%) had grade 3 left ventricular diastolic function. There were significant differences between the observation group and the control group in IVRT (114.97±10.16 vs 72.86±8.75, P<0.05), Ea/Aa (0.79±0.11 vs 1.3±0.25, P<0.05), and A' value (5.21±1.03 vs 5.02±0.82, P<0.05). In the observation group, IVRT, Ea/Aa, and A' value for left ventricular diastolic dysfunction were correlated with the development of acute cerebral infarction (r=0.53, 0.61, and -0.59).Conclusions Left ventricular function dysfunction is associated with hypertension in young adults, and left ventricular diastolic dysfunction may be an independent predictive factor for acute cerebral infarction in young hypertensive patients.