Objective To evaluate the accuracy of hematoma volume measurement using computed tomography (CT) reports in hypertensive intracerebral hemorrhage (HICH).Methods The head CT reports of 117 HICH patients were retrospectively analyzed. After collecting the raw scan data, 3D Slicer was used to reconstruct the three-dimensional (3D) structure of intracerebral hematoma and accurately calculate the hematoma volume. The size of hematoma calculated by 3D Slicer was grouped and statistically compared with that in CT reports to evaluate the deviation of hematoma volume in the department of radiology.Results With 3D Slicer, both 3D reconstruction and volume calculation of the raw head CT scan data of the 117 HICH patients were finished in a short time (range 21.98-242.4 s, mean 78.57±40.91 s); the amount of bleeding ranged from 0.62 ml to 166.03 ml, with a mean of 33.79±3.12 ml. In contrast, according to the CT reports, the amount of bleeding ranged from 1 ml to 190 ml, with a mean of 37.66±3.48 ml. There was a significant difference between the results of the two measurement methods, and the degree of deviation was not significantly correlated with hematoma volume.Conclusions With 3D Slicer, 3D reconstruction of hematoma and accurate calculation of its volume can be finished in a short time, and the operation is simple and easy. It can provide an accurate hematoma volume basis for the selection of therapeutic strategy for HICH.