Objective To investigate the value of end-to-end anastomosis of the common carotid artery (CCA) in microtechnique training for beginners.Methods A total of 53 neurosurgeons who came from different regions of China and did not receive professional microtechnique training were selected. A total of 116 male Sprague-Dawley rats were randomly selected. End-to-end anastomosis of the CCA was performed; the patency of the blood vessels, time for anastomosis (from the placement of the clamp to the release of the clamp), and number of stitches for anastomosis were observed immediately after anastomosis, and the patency of the blood vessels and survival rate were observed at 24 hours after anastomosis. Results Of all 116 rats, 7 (6.0%) died of anesthesia and 5 (4.3%) died of hemorrhage, resulting in a total of 104 valid cases. The mean number of stitches was 6.32 and the mean time for anastomosis was 64.82 minutes. The patency rate of blood vessels was 85.6% (89/104) immediately after anastomosis and 50.0% (52/104) on the next day, and the survival rate was 100% (104/104) on the next day.Conclusions There is a high patency rate of blood vessels immediately and the next day after the end-to-end anastomosis of the CCA, as well as a high survival rate after anastomosis. Therefore, it can be used as an appropriate animal model for microtechnique training for beginners in the department of neurosurgery.