Abstract:Objective To investigate the predictive value of saccade latency for delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (SAH).Methods A total of 110 patients with SAH who received treatment in our hospital from January 2012 to December 2016 were selected as study subjects. According to the presence or absence of concurrent DCI within 30 days after admission, they were divided into DCI group (n=40) and non-DCI group (n=70). Univariate and multivariate unconditional logistic regression analyses were used to investigate the risk factors for DCI in patients with SAH.Results The diagnostic cut-off values of saccade frequency, total time of saccade, mean time of single saccade, total amplitude of saccade, mean amplitude of saccade, mean saccade speed, and saccade latency for DCI after SAH were 2.65 times/s, 1685.45 ms, 39.03 ms, 553.25°, 8.05°, 118.35°/s, and 375.42 ms, respectively. The univariate and multivariate logistic regression analyses showed that Hunt-Hess grade ≥ Ⅲ, Fisher grade ≥ Ⅲ, degree of hydrocephalus (moderate or severe), and saccade latency ≥ 375.42 ms could increase the risk of DCI after SAH (P<0.05).Conclusions Saccade latency can predict the development of DCI after SAH.