Objective To explore the prevalence of restless legs syndrome (RLS) in patients with Parkinson's disease (PD) in China, and to compare the prevalence of RLS between PD patients and the general population.Methods The cross-sectional and case-control studies on the prevalence of RLS among PD patients in China were collected by a computerized search of Wanfang Data, CNKI, VIP, PubMed, and Web of Science. Eligible studies were used for the analysis of the prevalence of RLS among PD patients in China by Stata 12.0.Results A total 34 studies were enrolled and divided into IRLSSG group (n=7), NMS group (n=16), PDSS group (n=4), and other group (n=7) based on diagnostic criteria. According to the results of the meta-analysis, the prevalence rates of RLS among PD patients in all the studies, the IRLSSG group, the NMS group, the PDSS group, and the other group were 33%, 23%, 44%, 13%, and 28%, respectively. The prevalence of RLS was significantly higher in PD patients than in the general population (odds ratio=4.65, 95% confidence interval:2.39-9.03, P<0.001).Conclusions The prevalence of RLS among PD patients in China is 33%, which varies due to different diagnostic criteria. NMS is an effective approach for initial screening for RLS. IRLSSG is recommended for the diagnosis of RLS in PD patients. The prevalence of RLS is significantly higher in PD patients than in the general population in China.