Objective To investigate the surgical methods for microsurgical resection of intraspinal tumors via hemilaminectomy and their clinical effects.Methods A retrospective analysis was performed for the clinical data of 89 patients with intraspinal tumors who underwent microsurgical resection via hemilaminectomy in our hospital from January 2013 to April 2016. The bone window for hemilaminectomy was 1.0-1.5 cm in size and ranged from 1 to 9 segments. The surgical effect was evaluated based on the Frankel grade before and after surgery.Results Of all patients, 85 achieved total resection of tumors and 4 had near-total resection. There were varying degrees of improvement in neurological function after surgery. The patients were followed up for 5-24 months; cervical/thoracic/lumbar MRI and X-ray or CT showed no spinal deformity and there was good safety; one patient experienced recurrence of spinal meningioma.Conclusions Hemilaminectomy has the advantages of little surgical trauma and fast postoperative recovery and can best maintain spinal stability. Therefore, it can be used for resection of intraspinal tumors.