Objective To investigate the safety and efficacy of low-profile visualized intraluminal support (LVIS) stent-assisted embolization in the treatment of intracranial aneurysm.Methods A retrospective analysis was performed on the clinical data, endovascular treatment methods, and clinical outcome of 20 patients with 20 intracranial aneurysms who were treated with LVIS stent-assisted embolization. The degree of aneurysm embolization was evaluated according to the Raymond classification, and the clinical outcome was evaluated using the modified Rankin Scale (mRS).Results The stent release was satisfactory in all patients. Immediate postoperative angiography showed that Raymond grade I embolization was achieved in 15 patients (75%), Raymond grade II embolization in 4 patients (20%), and Raymond grade III embolization in 1 patient (5%). After 3-12 months of follow-up for 18 aneurysms, no recurrence was observed; the imaging results showed that 16 (88.9%) of the 18 aneurysms were cured and 2 (11.1%) remained stable. And 15 of the 18 patients had a good clinical outcome (mRS score 0-2).Conclusions LVIS stent-assisted coil embolization is safe and feasible. It can improve the embolization rate and reduce the recurrence rate of aneurysms. However, the long-term clinical effect needs to be confirmed by further studies with a large sample size and a summary of clinical experiences.