Objective To investigate the clinical characteristics, pathogenesis, treatment, and prognosis of post-traumatic cerebral infarction in children.Methods A retrospective analysis was conducted on 17 children treated in our hospital for post-traumatic cerebral infarction from 2011 to 2016.Results All of the 17 patients were followed up for 1 month to 5 years or more. During hospitalization, 30% of the patients recovered almost completely, while 70% had partial recovery of functions with mild limb movement disorder. After discharge from the hospital, the patients received rehabilitation treatment including hyperbaric oxygen therapy and functional training, and their brain function recovered completely. During the follow-up period, muscle strength was used as a test index for recovery of the patients. The t-test analysis of all 17 cases showed a significant difference between their muscle strength pre- and post- treatment (t=2.2, P<0.05), indicating that the muscle strength returned to normal.Conclusions The practice showed that although the onset of post-traumatic cerebral infarction in children is sudden and the condition is serious, with early active intervention and comprehensive treatments, their symptoms are partially or completely relieved, their functions recover quickly, and the prognosis is mostly good.