Objective To investigate the correlation between anthropometric data (height, weight, and waist circumference) and risk factors for silent lacunar infarction (SLI) and their clinical values.Methods The outpatients who were physically examined in our hospital from January 2014 to June 2014 had cranial magnetic resonance imaging (MRI). Comparison and analysis of age, height, weight, and waist circumference were made between 46 cases with SLI and 46 healthy controls at the same age.Results The waist circumference and waist circumference/height in the SLI group were significantly increased compared with those in the control group (P<0.05). There were no significant differences in height, weight, and body mass index between the two groups (P>0.05).Conclusions Waist circumference and waist circumference/height are significantly correlated with the occurrence of SLI and can become clinical monitoring parameters.