蒙特利尔认知评估量表和简易精神状态量表在帕金森病轻度认知功能障碍筛查中的应用
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任惠(1963-),女,教授,硕士生导师,主要从事癫痫、帕金森病研究.Email:rh-3338@163.com.

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Values of Montreal Cognitive Assessment Scale and Mini-Mental State Scale in detection of Parkinson's disease with mild cognitive dysfunction
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    摘要:

    目的 探讨蒙特利尔认知评估量表(MOCA)和简易精神状态量表(MMSE)在帕金森病轻度认知功能障碍(PDMCI)筛查中的应用.方法 采用随机抽样方法,应用MOCA和MMSE对75例诊断为PDMCI患者、帕金森病认知功能正常(PDN)患者180例和健康患者145例进行评估,比较二者筛查PDMCI的敏感性和特异性.结果 在文盲组MMSE的敏感性为93.10%,特异性为100%,而MOCA的敏感性仅为0%,特异性为92.72%;在小学组MMSE的敏感性为87.50%,特异性为100%,而MOCA的敏感性为41.67%,特异性为79.17%;在初中及以上学历组MMSE的敏感性为27.27%,特异性为100%,MOCA的敏感性为90.91%,特异性为85.71%.结论 MOCA适合初中及以上学历的PDMCI筛查工具,MMSE适合初中以下学历PDMCI筛查工具.

    Abstract:

    Objective To investigate the values of Montreal Cognitive Assessment Scale (MoCA) and Mini-Mental State Examination (MMSE) in detecting Parkinson's disease (PD) with mild cognitive impairment (PDMCI).Methods Random sampling was used to select 75 PDMCI patients, 180 PD patients with normal cognitive function, and 145 healthy controls. These subjects were screened by MoCA and MMSE for PDMCI, and the two scales were compared in terms of sensitivity and specificity.Results In the illiterate group, MMSE had a sensitivity of 93.10% and a specificity of 100%, versus 0% and 92.72% for MoCA. In the primary school group, MMSE had a sensitivity of 87.50% and a specificity of 100%, versus 41.67% and 79.17% for MoCA. In the junior high school and above group, MMSE had a sensitivity of 27.27% and a specificity of 100%, versus 90.91% and 85.71% for MoCA.Conclusions MoCA is suitable for PDMCI detection in people with degrees of junior high school and above, while MMSE for people with degrees below junior high school.

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王立安, 庞爱兰, 张林明, 任惠456.蒙特利尔认知评估量表和简易精神状态量表在帕金森病轻度认知功能障碍筛查中的应用[J].国际神经病学神经外科学杂志,2014,41(1):16-19111WANG Li-An, PANG Ai-Lan, ZHANG Lin-Ming, REN Hui222. Values of Montreal Cognitive Assessment Scale and Mini-Mental State Scale in detection of Parkinson's disease with mild cognitive dysfunction[J]. Journal of International Neurology and Neurosurgery,2014,41(1):16-19

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  • 收稿日期:2013-10-08
  • 最后修改日期:2014-01-15
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  • 在线发布日期: 2014-02-28
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