Objective To investigate the correlation of brain fluorodeoxyglucose (FDG) positron emission computed tomography (PET) findings with seizure type, electroencephalography (EEG) abnormality, and surgical outcome in children with epilepsy. Methods A retrospective study was conducted on the brain ¹⁸F-FDG PET findings of 71 children, who were diagnosed with epilepsy by clinical examination, EEG, and imaging examination and received surgical treatment, to investigate the glucose metabolism in brain cells in the epileptic focus. According to the PET findings, the 71 patients were divided into three hypometabolism groups, including 33 cases with hypometabolism in a single lobe, 28 cases with hypometabolism in two lobes, and 10 cases with hypometabolism in more than two lobes. The clinical data of the 71 patients, such as course of disease, sex, age, seizure type, EEG data, and surgical outcome, were collected. The chi-square test was used for comparing the three groups in terms of the constituent ratios in each item of the clinical data. Results No significant differences in age and sex were seen between the three hypometabolism groups, but there were significant differences in seizure type, EEG abnormality, and surgical outcome between them (P<0.05). Conclusions Brain FDG PET findings are significantly correlated with surgical outcome, seizure type, and EEG abnormality in children with epilepsy.