Objective To study the therapeutic efficacy and other considerations used minimally invasive puncture drainage to treat chronic subdural hematoma.Methods From August 2008 to July 2012 total 35 chronic subdural hematoma patients were treated with minimally invasive puncture drainage, followed up the discharged patients and summarizes the treatment effect.Results 35 patients were succeed puncture at one time without serious complications, symptoms were significantly improved, 27 cases cavity disappeared before discharge hematoma (77%), 8 cases have small subdural effusion (23%). Periodic review of discharge head CT, without recurrence cases.Conclusions The minimally invasive puncture drainage in the treatment of chronic subdural hematoma is simple operation, less complications, patients recover quickly, widely applicable.