Objective To observe the operative effecacy in patients with medically intractable TLE associated with HS, by Magnetic Resonance Imaging. Methods Selecting patients with MRI revealed HS and ascertained Histopathologically followed at least 2 years by phone or checking electroencephalogram regularly included in this experiment, analyzing consequence by using spss 17.0 systerms.Results Patients with HS and interictal epileptic discharges were congruenctic obvious operation result and in the following 6 years patients were satisfied with the operation were 90.66%,88.57%,88.25%,86.20%,72%,69.04% respectively. Conclusions The anterior temporal lobectomy should be performed in the patients with TLE accompanied with HS, if the EEG shows that there are epileptic discharges in the ipsilateral temporal lobe.