目的 总结中分化松果体实质肿瘤的临床特点和治疗。方法 回顾性分析6例中分化松果体实质肿瘤病人的临床资料，3例行Poppen入路，2例行胼胝体穹隆间入路，1例经侧脑室三角区入路。术后4例患者放疗，2例行化疗。结果 肿瘤全切除1例，次全切除4例，部分切除1例。术后围手术期死亡1例，随访5例患者，死亡1例，余4例存活。结论 中分化松果体实质肿瘤比较罕见，诊断主要依靠临床表现、影像学及组织病理特征。治疗首先手术联合术后辅助放疗、化疗。
Objective To summarize the clinical features and treatment of pineal parenchymal tumors of intermediate differentiation (PPTIDs).Methods A retrospective analysis was performed on the clinical data of 6 patients with PPTIDs. Poppen approach was used in 3 cases, transcallosal interforniceal approach was used in 2 cases, and transtrigone lateral ventricle approach was used in 1 case. After operation, 4 patients received radiotherapy, and 2 patients received chemotherapy.Results All the tumors were surgically removed, including total resection in 1 case, subtotal resection in 4 cases, and partial resection in 1 case. After operation, 1 patient died during the perioperative period; among 5 patients followed up, 1 died, and 4 survived.Conclusions PPTIDs are rarely seen. The diagnosis of PPTIDs mainly depends on clinical manifestations, radiological findings, and histopathological features. The patients with PPTIDs should be treated by microsurgery combined with postoperative radiotherapy and chemotherapy.
黄冠又, 张岩, 汤劼, 吴震, 张力伟, 张俊廷456.中分化松果体实质肿瘤（附6例报告）[J].国际神经病学神经外科学杂志,2013,40(4):317-320111Huang Guan-You, Zhang-Yan, Tang Jie, Wu Zhen, Zhang Li-Wei, WU Junting222. Pineal parenchymal tumors of intermediate differentiation：a report of six cases[J]. Journal of International Neurology and Neurosurgery,2013,40(4):317-320复制